介绍:Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that divferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
PE标记CTAGE4,皮肤T细胞淋巴瘤相关抗原4抗体Function:
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein divferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
抗体名称:PE标记CTAGE4,皮肤T细胞淋巴瘤相关抗原4抗体-产品介绍
抗体别名:AHD 4; AHD C; Ahd4; AHDC; AL3A1_HUMAN; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase 3 family mdivber A1; Aldehyde dehydrogenase 3 family, mdivber A1; Aldehyde dehydrogenase 3A1; Aldehyde dehydrogenase; Aldehyde dehydrogenase class 3; Aldehyde dehydrogenase dimeric NADP divferring; Aldehyde dehydrogenase family 3 mdivber A1; Aldehyde dehydrogenase family 3 subfamily A1; Aldehyde dehydrogenase isozyme 3; Aldehyde dehydrogenase type III; Aldehyde dehydrogenase, dimeric NADP divferring; ALDH 3; ALDH 3A1; ALDH III; ALDH3 A1; ALDH3; ALDH3A 1; Aldh3a1; ALDHIII; dimeric NADP-divferring; MGC10406; Stomach aldehyde dehydrogenase; Tumor associated aldehyde dehydrogenase tumor ALDH.
PE标记CTAGE4,皮肤T细胞淋巴瘤相关抗原4抗体抗体种属:兔来源抗体,鼠来源抗体
相关标记:Alexa Fluor 350 标记、Alexa Fluor 488 标记、Alexa Fluor 555 标记、Alexa Fluor 647 标记、AP标记、APC标记、Biotin标记、Cy3标记、Cy5标记、Cy5.5标记、Cy7标记、FITC标记、Gold标记、HRP标记、PE标记、PE-Cy3标记、PE-CY5标记、PE-CY5.5标记、PE-CY7标记、RBITC标记.
抗体的交叉反应:人,小鼠,大鼠,鸡,狗,猪,羊,牛,兔等......(需来电咨询)
PE标记CTAGE4,皮肤T细胞淋巴瘤相关抗原4抗体抗体的应用:
可以用于做石蜡切片免疫组化,冰冻切片免疫组化,Elisa,WB,免疫荧光,流式细胞术等实验。
(公司长期备有做免疫组化与WB所需的二抗及相关试剂)
(不同抗体所适用的实验有不同,具体详情可添加客服QQ,索取说明书)
Western Blotting(WB)、ELISA、Immunohistochdivistry(IHC-F、IHC-P)、Immunofluorescence(IF)、Immunodivcipitation(IP)、ICC、Flow Cytometry(FCM)
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
抗体修复方式:
修复液:0.01M 枸橼酸(pH6.0)或者0.05M EDTA(pH8.0)
抗体修复方法:
方法1:沸水浴修复,将盛有修复液和玻片的烧杯置于沸水浴环境,保持外部沸腾状态15min,自然冷却至室温;
方法2:微波修复,将盛有修复液和玻片的烧杯置于微波炉中,高火5min,停火3min,中火5min,自然冷却至室温。
抗体常用试剂配制:
DAB溶液配制:(组化及Western blot 显色)
称DAB 30mg,用0.05mol/L pH7.6 Trs-HCL缓冲液100ml溶解,如有沉淀,过滤后使用,一般新鲜配制使用;
使用前加入1% H2O21ml至1.5ml,H2O2浓度为0.01%,混均后使用。
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